Tuesday, March 31, 2009

Propranolol


Propranolol (INN) is a non-selective beta blocker mainly used in the treatment of hypertension. It was the first successful beta blocker developed. It is the only drug proven effective for the prophylaxis of migraines in children. Propranolol is available in generic form as propranolol hydrochloride, as well as an AstraZeneca and Wyeth product under the trade names Inderal, Inderal LA, Avlocardyl (also available in prolonged absorption form named "Avlocardyl Retard"), Deralin, Dociton, Inderalici, InnoPran XL, Sumial (depending on marketplace and release rate).

Propranolol is indicated for the management of various conditions including:[1]
Hypertension
Angina pectoris
Tachyarrhythmias
Myocardial infarction
Control of tachycardia/tremor associated with anxiety, hyperthyroidism or lithium therapy.
Essential tremor
Migraine prophylaxis
Cluster Headaches prophylaxis
Tension headache (Off the label use)
Tetralogy of Fallot
Phaeochromocytoma (along with α blocker)
There has been some experimentation in psychiatric areas:[2]
Treating the excessive drinking of fluids in psychogenic polydipsia,[3][4]
Antipsychotic-induced akathisia,[5]
Aggressive behavior of patients with brain injuries[6]
Post-traumatic stress disorder
Glaucoma

1 comment: